Advances in Brief activity in a number of in vitro and in vivo mammary cancer models utilizing ZR-75-1, MCF-7, and MDA-MB-468 human cell lines (11—
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چکیده
in Refs. 11—13)Octreotide has demonstrated significant antitumor
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Cell Kinetic Study of Tamoxifen Treated MCF-7 and MDA-MB 468 Breast Cancer Cell Lines
Apoptosis could be a major mechanism of antitumor effect of tamoxifen. Therefore this study is designed to characterize the kinetic behavior of tamoxifen-induced apoptosis in the estrogen receptor positive (ER+) and negative (ER-) cell lines, MCF-7 and MDA-MB-468. Frequency of cell death was examined by trypan blue and acridine orange staining. Annexin V-Fluorescein/PI was used in flow cytometr...
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